Van de Ven Double Ends The Toffees' Unbeaten Streak at Brand New Home Ground
The Dutch defender emerged as the initial backline player to score twice in a English top-flight match for Tottenham since Jan Vertonghen in spring 2013.
Match summary
The Spurs defender heads into the net twice in first half
The home side's defender has equalizer disallowed after video check
Senegalese midfielder nets third in dying moments
The defeat is the Merseyside club's initial at their new ground
The Tottenham defender scored on two occasions as Spurs prolonged their unbeaten run in away games in the top division and handed Everton their first defeat at their new home.
Everton were undefeated in their last five matches at their new ground at the dockside location, having left their historic home behind after 133 years at the end of last season.
But Tottenham's leader Van de Ven pounced on two occasions from corners in the opening 45 minutes to put their impressive record at risk, and they were failed to mount a comeback before Pape Matar Sarr - set up by ex-Everton forward Richarlison - nodded in a final goal to seal the victory.
Jake O'Brien believed he had levelled the tally five minutes after Van de Ven's opener, directing a bullet header past the Spurs keeper from an Everton corner.
Beto, meanwhile, missed a number of opportunities, while Vicario made a succession of excellent stops to ensure the London club went five away games without defeat in the Premier League.
But the video assistant referee intervened, instructing Craig Pawson to review the goal on the pitchside monitor and the official decided that Jack Grealish and the attacker were in offside positions and had interfered with the Spurs keeper.
This victory elevates Thomas Frank's team into third place in the Premier League, a handful of points off north London rivals and table-toppers Arsenal.
Everton stay in 14th position and sit half a dozen points ahead of the relegation zone.
Tottenham analysis: Van de Ven excels in role at both ends of pitch
Following a uninspiring midweek display in the European competition against the French side, where they managed a only attempts on goal, the manager opted for Randal Kolo Muani up front instead of ex-Everton forward the Brazilian.
The summer signing was failed to influence the game before being replaced for Richarlison after 60 minutes on the pitch, but it turns out he proved unnecessary in the final outcome.
Centre-back the Dutchman transformed into an attacking force to be feared.
Tottenham's opening strike came from a well-worked corner routine, with Rodrigo Bentancur heading the ball toward the face of goal for an free Van de Ven to head home.
And the captain - stepping up as captain in Cristian Romero's absence - notched his next goal in first-half stoppage time as he outjumped the England keeper to head home.
The Dutchman was equally impressive in defensive duties, combining effectively with Kevin Danso as the pair handled excellently with the 34 crosses sent their way by the opposition.
Toffees breakdown: Everton lacking striker's instinct
Everton's new home had been a happy hunting ground, but it appears the freshness may have worn off somewhat and supporters headed to the exits after the midfielder's third for Spurs.
The break in the team's winning streak at home won't be a massive worry for David Moyes, but their striker situation are.
The forward and Thierno Barry - the Everton's pair of established strikers - had scored just one league goal between them before the weekend's outing.
And they were failed to add to that poor tally on a damp and dreary night on Merseyside.
Beto's form was epitomized when he opted to bicycle-kick a golden opportunity from close range, even with having space and time to readjust for a simpler attempt that would have tested the keeper.
Barry, too, was unable to make an impact after replacing the starter in the second half.
It was not for a lack of chance. The majority of Everton's offensive moves came through the winger and the forward, who relentlessly whipped threatening balls into the Tottenham box.
What next for these two sides?
Everton: Moyes' men travel to Sunderland in the top flight on early November at 8 PM.
Tottenham: Spurs travel to Newcastle's ground on Wednesday, 29 October for their next round Carabao Cup tie against Newcastle.